After Embryo Transfer Day By Day Symptoms

After Embryo Transfer Day By Day Symptoms banner

Published on: April 9, 2025

Author: Admin

If you are scrolling this page, then it’s most likely that you are undergoing the in vitro fertilization (IVF) treatment. The treatment is where the sperm and eggs are fertilized in the laboratory. The fertilized eggs are then transferred into the uterus. Everybody knows about the process until this. But, have you ever wondered what will happen after the embryo transfer, apart from the two-week waiting period?

Here we are with a comprehensive guide that includes what happens after embryo transfer day by day symptoms, the positive and negative signs of implantation, and reasons for the two weeks of the waiting period after the embryo transfer in the in vitro fertilization (IVF) treatment. Let’s get started!

After Embryo Transfer Day By Day Symptoms

While implantation symptoms after embryo transfer in IVF treatment may generally differ from person to person, the following table lists details of the implantation process and its symptoms.

Days Process Symptoms
Day 0 The embryo is transferred. Mild cramping and discomfort are caused because of the embryo transfer procedure.
Day 1–2 The embryo begins to shed its outer shell and tries to attach itself to the uterus. You may feel more tired or exhausted due to the effects of fertility medications.
Day 3 The embryo begins to implant. Some women report that they experience mild bloating or the feeling of fullness during this period.
Day 4 Implantation continues. You may notice the light spotting as implantation continues.
Day 5 Implantation is completed. Cells start to become placenta. The fetus continues to grow. You may experience breast tenderness, mild cramping, or changes in the cervical mucus.
Day 6 hCG hormone starts to signal the body of the growing fetus. The hormone also starts to rush into the bloodstream. You may have mood swings because of the hormonal shifts in the maternal body.
Day 7–8 As fetal growth continues, the placenta continues to secrete hCG hormone. The rising hormones may cause a heightened sense of smell, and morning sickness.
Day 9–10 Noticeable symptoms may start to appear. Food aversions, mood swings, heightened sense of smell, and morning sickness can all be the sign of implantation.
Day 11–12 hCG hormone levels are high enough to be detected in the blood test. You may experience increased hunger or thirst because of the rising hormones in the maternal body.

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Positive Signs After Embryo Transfer

While a woman’s body changes after embryo transfer drastically in an IVF procedure, remember that it’s not mandatory to experience all signs and symptoms after implantation. The absence of symptoms can also indicate the successful implantation. However, the early pregnancy symptoms and premenstrual symptoms can be confusing and are hard to distinguish. Hence, it is highly suggested to wait patiently for those two weeks until your healthcare physician confirms the pregnancy through the beta blood test.

Following are some of the common positive signs after embryo transfer. They are:

Light Spotting or Bleeding

Light spotting is often caused by the implantation bleeding. The spotting happens when the embryo attaches to the uterine lining or endometrium. This is the earliest possible sign of a successful pregnancy.

Cramping and Pelvic Pain

Cramping and pelvic pain are the other most common positive signs of early pregnancy. These happen as the maternal uterus is getting adjusted with the implanted embryo.

Fatigue and Tiredness

Fatigue and tiredness are caused by the rapid hormonal shifts in the maternal body. They are one of the most common positive signs of successful implantation.

Tender or Sore Breasts

Tender or sore breasts are also among the common early signs of pregnancy. These happen as the maternal body is getting prepared for breastfeeding. This is caused by hormonal changes and the enhanced blood flow to the breasts.

Nausea

Nausea is otherwise known as morning sickness. These happen because of the hormonal shifts due to the successful pregnancy.

Frequent Urination

The hormonal fluctuations and an increased blood flow to the kidneys during pregnancy enhance the production of urine. This consequently leads you to urinate more frequently.

Changes in Vaginal Discharge

Noticeable changes in vaginal discharge are one of the after embryo transfer symptoms. The discharge may appear to be white in colour and slightly odorous. This can indicate the positive sign of successful implantation. However, if you notice the discharge because of infection, and have a sense of burning, or itching, this might have been caused by fertility medications. In such scenarios, seeking medical help is recommended.

Missed Periods

Missing your menstrual cycle or periods, especially if you have a regular cycle, can indicate a sign of successful implantation.

No Symptoms after your Embryo Transfer

Even if you experience no symptoms after embryo transfer in in vitro fertilization (IVF) treatment can still indicate the sign of successful implantation. The absence of above-mentioned embryo transfer day by day symptoms doesn’t necessarily need to be exhibited to confirm your pregnancy.

Negative Signs After Embryo Transfer

After an embryo transfer in an IVF procedure, just like positive signs of implantation, there are certain potential signs that indicate the sign of unsuccessful implantation. These are considered negative signs after embryo transfer and may include:

Absence of Pregnancy Symptoms

Even though the lack of pregnancy symptoms can still indicate successful implantation, it is not the case in every scenario. If a woman doesn’t notice any pregnancy symptoms within a few weeks after the embryo transfer, it can sometimes be an indication that the implantation is unsuccessful. In such cases, it is recommended to seek medical help and discuss further treatment plans with your physician.

Vaginal Bleeding

While light spotting is an indication of implantation bleeding, heavy bleeding can be an indication of unsuccessful implantation.

Intense Cramping or Discomfort

Though mild cramping is normal, more intense cramping or severe discomfort needs to be evaluated by the fertility expert. This can be a troubling symptom of unsuccessful implantation.

Negative Pregnancy Test

The negative pregnancy test result after the two-week waiting period of the IVF procedure can significantly indicate the sign of unsuccessful implantation. However, it is highly recommended to have a consultation with your fertility expert and confirm the result through the blood test.

Reasons for the Two-Week Wait for a Blood Test

The first pregnancy test after the two-week waiting period of embryo transfer in IVF treatment!

After the waiting period, the first thing your fertility expert performs is the blood test. The blood test is performed to detect the presence of beta hCG in your blood. As you know, the hCG is an essential hormone that confirms your pregnancy. In addition, its increasing level determines the strength and progress of the growing fetus.

Following are the tabular details of the normal range for human chorionic gonadotropin (hCG) hormone levels throughout the pregnancy.

Gestational Age hCG Value (mIU/mL)
1 week 5 – 50
2 weeks 40 – 1,000
3 weeks 100 – 5,000
4 weeks 600 – 10,000
5 – 6 weeks 1,500 – 100,000
7 – 8 weeks 16,000 – 200,000
2 – 3 months 12,000 – 300,000

There are certain reasons why your fertility expert recommends you wait for those two weeks. They are:

Higher Accuracy

The two-week waiting period after the embryo transfer in the IVF procedure can significantly provide the most accurate results. This is because the hCG levels in your blood can be detected as low as 1-5 mIU/mL in the blood test. The home pregnancy test, which is detected through urine cannot detect the lowest level of hCG in your blood.

Early Detection

Since the blood test can detect the lowest level of hCG hormones, it ensures to confirm the successful implantation much prior.

Comprehensive Monitoring

Furthermore, the comprehensive monitoring of implantation through hCG blood test can help to determine the health of the growing fetus. This facilitates the fertility expert to make the most informed decisions regarding potential interventions and pregnancy management.

Frequently Asked Questions

You might generally start to notice the pregnancy symptoms around days 4 - 7 after the embryo transfer. The symptoms may include mild cramping, breast tenderness, and so on.
You can enhance the health of the uterine lining or endometrium by including nutrient-rich foods such as antioxidants, L-arginine, and omega-3s. In addition, you can practise moderate exercise, stress management, acupuncture, and mild walking.
After a negative embryo transfer, many fertility experts suggest waiting for at least one menstrual cycle to complete. This allows your body and mind to recover and prepare for further treatment. However, the timeline is usually recommended by your physician based on the patient’s health.
The answer to the question is yes. You will likely experience lower back pain typically after an embryo transfer. This happens because of hormonal fluctuations, the body’s response to the IVF procedure, and physical strain.
It is highly suggested to seek medical help when you notice the following symptoms after embryo transfer: severe cramping, heavy vaginal bleeding, dizziness, persistent high body temperature, fainting, or blood clots or tissues passing through the vagina.

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